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drug tolerance
drug tolerance Drug tolerance is a reduced response to a drug after it has been used repeatedly, so larger amounts are needed to produce the same effect that a smaller amount once did.
Drug tolerance is a reduced response to a drug after it has been used repeatedly, so larger amounts are needed to produce the same effect that a smaller amount once did. It can result from changes in how the body processes the drug or from cellular, physiological, or behavioral adaptation to its effects.