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Pick Disease of the Brain

Pick Disease of the Brain Pick disease of the brain is a rare form of dementia that is sometimes familial.

Pick disease of the brain is a rare form of dementia that is sometimes familial. It is marked by aphasia, apraxia, confusion, anomia, memory loss, and personality deterioration, with circumscribed atrophy at the frontal and temporal poles and greatest neuronal loss in the hippocampus, entorhinal cortex, and amygdala; some ballooned cortical neurons contain Pick bodies.