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microtubule

microtubule A microtubule is a cellular structure made through tubulin polymerization, and it can be disrupted by compounds that bind tubulin.

A microtubule is a cellular structure made through tubulin polymerization, and it can be disrupted by compounds that bind tubulin. Because blocking microtubule formation can halt cells in the G2–M phase, microtubules are important targets in cancer research.

Sources

Drafting source: Herman Jean; Vanstreels Els; Bardiot Dorothée; Prota Andrea E.; Gaillard Natacha; Gao Ling-Jie; Vercruysse Thomas; Persoons Leentje; Daems Tinne; Waer Mark; Herdewijn Piet; Louat Thierry; Steinmetz Michel O.; De Jonghe Steven; Sprangers Ben; Daelemans Dirk. 3-nitropyridine analogues as novel microtubule-targeting agents. 2024; DOI 10.1371/journal.pone.0307153; article XML SHA-256 a43ab75717a36269572fd3ad75cf6bc67b5b7d0cbe7efdc4927c6eb48aeea1de. “3-nitropyridine analogues as novel microtubule-targeting agents” (10.1371/journal.pone.0307153).
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PsychTerms (psychterms.org), CC BY 4.0, version 1. “microtubule.” Development preview.

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microtubule

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Sources

Cite this entry