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mental health

Judged: two independent readers; copy check clear.

TSD

TSD TSD stands for total sleep deprivation, meaning staying awake for a full night without sleep.

TSD stands for total sleep deprivation, meaning staying awake for a full night without sleep. In depression research, one night of TSD has been noted to produce a rapid but short-lived improvement in mood in many patients, making it useful for studying fast antidepressant effects.