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topiramate

topiramate Topiramate is a pharmacologic substance with anticonvulsant effects.

Topiramate is a pharmacologic substance with anticonvulsant effects. It appears to reduce seizures by blocking certain glutamate receptor activity, increasing GABA-related activity, and helping stabilize overexcited nerve cell signaling in the central nervous system.

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Sources

Drafting source: NCI Thesaurus. Flat export snapshot 2026-10-18. “Topiramate” (C47764).
CC-BY-4.0 · Definition uses new wording; original source retains its stated licence. · Source snapshot SHA-256: b27ca135beadd46c343d248135377c5077c5447fe11b93803bfab866b84fcd38

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PsychTerms (psychterms.org), CC BY 4.0, version 1. “topiramate.” Development preview.

Version 1 · SHA-256: 90b545c61c15697bfed8168a3a9d944366b89d2152750c32dc3306752cac6772

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