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Tay–Sachs disease
Tay–Sachs disease Tay–Sachs disease is an inherited neurodegenerative disorder passed in an autosomal recessive pattern that begins in infancy, often with an unusually strong startle response and later progresses to paralysis, dementia, and blindness.
Tay–Sachs disease is an inherited neurodegenerative disorder passed in an autosomal recessive pattern that begins in infancy, often with an unusually strong startle response and later progresses to paralysis, dementia, and blindness. It results from mutation affecting hexosaminidase A, leading to lipid buildup in ganglion cells, and has a strong association with Ashkenazic Jewish ancestry.