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biological

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spongiform encephalopathy

spongiform encephalopathy Spongiform encephalopathy is a transmissible brain disease caused by a protein that triggers abnormal folding of normal proteins.

Spongiform encephalopathy is a transmissible brain disease caused by a protein that triggers abnormal folding of normal proteins. It produces sponge-like changes in the brain with loss of nerve cells and no inflammatory response, typically develops after a long incubation period, then progresses quickly and is fatal.