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biological

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retrograde degeneration

retrograde degeneration Retrograde degeneration is a disease-related change that develops in the part of a neuron nearest an axon injury, affecting both the axon and the cell body.

Retrograde degeneration is a disease-related change that develops in the part of a neuron nearest an axon injury, affecting both the axon and the cell body. It is marked by central chromatolysis, including swelling of the cell, loss of Nissl substance, and flattening and shifting of the nucleus.