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respiratory depression

respiratory depression Respiratory depression is a dangerous slowing and disruption of breathing, marked by reduced ventilation and rising carbon dioxide levels in the blood.

Respiratory depression is a dangerous slowing and disruption of breathing, marked by reduced ventilation and rising carbon dioxide levels in the blood. In the context of opioid use, it can progress to irregular breathing and apnea, making it a major cause of death in overdose.

Sources

Drafting source: Moss Laurence M; Algera Marijke Hyke; Dobbins Robert; Gray Frank; Strafford Stephanie; Heath Amy; van Velzen Monique; Heuberger Jules A A C; Niesters Marieke; Olofsen Erik; Laffont Celine M; Dahan Albert; Groeneveld Geert Jan. Effect of sustained high buprenorphine plasma concentrations on fentanyl-induced respiratory depression: A placebo-controlled crossover study in healthy volunteers and opioid-tolerant patients. 2022; DOI 10.1371/journal.pone.0256752; article XML SHA-256 1721fe7a99c056463a8f80f3b01d55935688019dfbc83fe15a75c3809f12a37f. “Effect of sustained high buprenorphine plasma concentrations on fentanyl-induced respiratory depression: A placebo-controlled crossover study in healthy volunteers and opioid-tolerant patients” (10.1371/journal.pone.0256752).
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PsychTerms (psychterms.org), CC BY 4.0, version 1. “respiratory depression.” Development preview.

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respiratory depression

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