Judged: two independent readers; copy check clear.
polysubstance dependence
polysubstance dependence Polysubstance dependence refers to a history of dependence involving more than one type or class of drug, rather than dependence on a single substance alone.
Polysubstance dependence refers to a history of dependence involving more than one type or class of drug, rather than dependence on a single substance alone. In this source, it is used to distinguish people with multiple-substance dependence from those with only heroin dependence, only amphetamine dependence, or no substance dependence history.