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nalmefene

nalmefene Nalmefene is a small-molecule mu opioid receptor antagonist that is used as an antidote for fentanyl and related opioid overdose.

Nalmefene is a small-molecule mu opioid receptor antagonist that is used as an antidote for fentanyl and related opioid overdose. It is structurally similar to naloxone but has a much longer elimination half-life in humans, about 11 hours, which may help extend reversal of opioid effects.

Sources

Drafting source: Averick Saadyah E.; Kassick Andrew J.; Song Daihyun; Zhang Borui; Vigliaturo Jennifer; Luengas Diego; Silva-Ortiz Pedro; Pravetoni Marco; Raleigh Michael D.. Evaluating the rate of reversal of fentanyl-induced respiratory depression using a novel long-acting naloxone nanoparticle, cNLX-NP. 2024; DOI 10.3389/fpsyt.2024.1366186; article XML SHA-256 d55b8f53034570215d662fae4d7827124c14a3ffcd216cf025d10ee96b0664c9. “Evaluating the rate of reversal of fentanyl-induced respiratory depression using a novel long-acting naloxone nanoparticle, cNLX-NP” (10.3389/fpsyt.2024.1366186).
CC-BY-4.0 · Definition uses new wording; original source retains its stated licence. · Source snapshot SHA-256: d55b8f53034570215d662fae4d7827124c14a3ffcd216cf025d10ee96b0664c9

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PsychTerms (psychterms.org), CC BY 4.0, version 1. “nalmefene.” Development preview.

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nalmefene

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Sources

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