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metachromatic leukodystrophy

metachromatic leukodystrophy Metachromatic leukodystrophy is an inherited disorder in which deficient arylsulfatase A leads to abnormal myelin development.

Metachromatic leukodystrophy is an inherited disorder in which deficient arylsulfatase A leads to abnormal myelin development. It has late infantile, juvenile, and adult forms, and can involve problems with walking, developmental or mental decline, seizures, and in adults psychotic symptoms and dementia.