Judged: two independent readers; copy check clear.
knockout
knockout A knockout is an organism, or an experimentally created model, in which a specific gene or enzyme has been disabled so its usual function is absent.
A knockout is an organism, or an experimentally created model, in which a specific gene or enzyme has been disabled so its usual function is absent. In this packet, knockout mice were made to lack particular kynurenine pathway enzymes in order to study the effects on metabolism and organ function.