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guanfacine

guanfacine Guanfacine is a non-stimulant medication that acts on alpha-2 adrenergic receptors and is used in children with ADHD to reduce symptoms.

Guanfacine is a non-stimulant medication that acts on alpha-2 adrenergic receptors and is used in children with ADHD to reduce symptoms. It has mild sedating effects and may be especially helpful for behavioral symptoms such as hyperactivity, but it is also associated with relatively poor tolerability because side effects often lead people to stop taking it.

Sources

Drafting source: El Masri Sahid; Kowalczyk Olivia S.; Chiu Tsz Hei; Criaud Marion; Lukito Steve; Mazibuko Ndabezinhle; Salazar de Pablo Gonzalo; Perez Rodriguez Violeta; Makos Orsolya; Lam Sheut-Ling; Westwood Samuel; Eaton-Turner Alexander; Bozhilova Natali; Conti Aldo; Santosh Paramala; Roessner Veit; Kohls Gregor; Mehta Mitul A.; Rubia Katya. Differential effects of a single dose of Lisdexamfetamine and Guanfacine on cognitive function in children with ADHD. 2025; DOI 10.3389/fpsyt.2025.1676472; article XML SHA-256 fe8eba2ca97c3a9598df6fdc03147b78a21f765e2b8b6529220e4102a0909f5e. “Differential effects of a single dose of Lisdexamfetamine and Guanfacine on cognitive function in children with ADHD” (10.3389/fpsyt.2025.1676472).
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PsychTerms (psychterms.org), CC BY 4.0, version 1. “guanfacine.” Development preview.

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guanfacine

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Sources

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