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group sequential design

group sequential design A group sequential design is a study design that includes planned checks of the data while the trial is still running, so the study can stop early if there is strong enough evidence of benefit while still controlling false-positive error rates.

A group sequential design is a study design that includes planned checks of the data while the trial is still running, so the study can stop early if there is strong enough evidence of benefit while still controlling false-positive error rates. In psychological research, this approach can affect power and can bias some effect estimates if the sequential nature of the design is not taken into account.