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diagnosis

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endophenotype

endophenotype An endophenotype is a measurable neurobiological, physiological, cognitive, or social-cognitive marker that serves as an intermediate link between a disorder’s underlying polygenic basis and its clinical symptoms.

An endophenotype is a measurable neurobiological, physiological, cognitive, or social-cognitive marker that serves as an intermediate link between a disorder’s underlying polygenic basis and its clinical symptoms. In psychology and psychiatry research, it refers to a marker expected to be heritable, relatively independent of current illness state, and to run within families alongside the disorder.