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mental health

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Depressive Disorder, Treatment-Resistant

Depressive Disorder, Treatment-Resistant Treatment-resistant depressive disorder is depression that does not improve after multiple antidepressant treatment attempts.

Treatment-resistant depressive disorder is depression that does not improve after multiple antidepressant treatment attempts. In this source, it means failing to respond to at least two trials of single antidepressants or to four or more trials using different antidepressant therapies.