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cross-tolerance
cross-tolerance Cross-tolerance is when long-term use of one drug makes a person less responsive to the effects of other drugs that act in a similar way, such as other mu-receptor agonists.
Cross-tolerance is when long-term use of one drug makes a person less responsive to the effects of other drugs that act in a similar way, such as other mu-receptor agonists. In this context, it can reduce physical dependence on those other drugs.