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clonidine
clonidine Clonidine is a centrally acting drug with blood-pressure-lowering effects.
Clonidine is a centrally acting drug with blood-pressure-lowering effects. It stimulates alpha-2 adrenergic receptors in the brain, which reduces norepinephrine release and sympathetic nerve activity, leading to lower blood pressure and heart rate; actions at imidazoline I1 receptors may also help.