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allosteric modulation

allosteric modulation Allosteric modulation is a change in how a protein complex works after a substance binds to it.

Allosteric modulation is a change in how a protein complex works after a substance binds to it. In this packet, negative allosteric modulation means the serotonin transporter’s activity is reduced, so it takes up less serotonin.

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Sources

Drafting source: NCI Thesaurus. Flat export snapshot 2026-10-18. “Paroxetine Mesylate” (C47653).
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PsychTerms (psychterms.org), CC BY 4.0, version 1. “allosteric modulation.” Development preview.

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